We all age. Its part of life.
But most of us hope that as we age, we can maintain the highest quality of life possible.
That we can keep as much of the energy, strength, and appearance we enjoy in youth.Hormones are key players in our ability to feel and look young as well as stave off the degenerative diseases of aging.
As we age, hormone levels change. Typically, the hormones we like at high levels fat burning, energy producing hormones will fall. And the hormones we like at low levels fat storing, energy depleting hormones tend to rise. With this change, we look and feel older.
This is when intervention with hormone optimization can be extremely beneficial. Human Growth Hormone (HGH) is one of these hormones. Unfortunately, it isnt available to everyone who needs it, largely due to its price tag. There is now a less expensive alternative.
One medication alternative to HGH is the use of Growth Hormone Releasing Factor129 NH2-acetate, orSermorelin, which has recently become available to physicians for use in Age Management Medicine.Sermorelin is an analog (similar molecule) of naturally occurring Growth Hormone-Releasing Hormone (GHRH) whose activity also declines during aging. Unlike injectable HGH that causes production of the bioactive hormone IGF-1 from the liver, sermorelin simulates your own pituitary gland to increase production and secretion of your own bodys HGH. Then the secreted HGH travels to the liver to cause production of IGF-1 so it can do its work for your body.
So basically, instead of injecting HGH, you inject sermorelin, which causes your body to secrete more of its own HGH.
When combined with exercise, Sermorelin is great for maintaining a healthy weight. The loss of HGH that occurs with aging is correlated with an increase in body fat and a decrease in muscle mass. The loss of HGH also slows down the bodys fat metabolism, which is why it is easier to put on weight as we start to age and harder to lose it. Sermorelin helps with all of that and more. It helps restore a more youthful metabolism, so that the food you do eat isnt converted into fat as easily. It also helps with improving muscle mass which in turn burns more calories when you are sedentary, and it helps burn abnormal fat that you already have. In general, its a great option for aging adults to help them maintain their weight. . HGH is highly beneficial in restoring a healthy Muscle/Fat ratio. It reduces fat from areas of the body such as the thighs and midsection while also encouraging the growth and development of new muscle fibers.
Sermorelin is also proven to be effective at helping adults restore a more normal sleep cycle. An abnormal sleep cycle and insomnia are both associated with weight gain. People who stay up for longer periods of time are more likely to eat to stay alert or out of boredom, and many sleep disorders and problems are associated with weight gain. Sermorelin has been reported to help adults improve their sleep within just days of starting the treatment, and by getting higher quality sleep and more sleep, it can be easier to maintain a healthy weight. Most adults need a minimum of 7 hours of sleep per night to be adequately rested, and if you are an aging adult with weight to lose as well as sleep problems, you may definitely want to consider starting Sermorelin therapy.
How is Sermorelin Used?
Sermorelin is administered by an injection under the skin with a tiny needle once daily prior to bedtime, just like HGH. The time of injection is important because sermorelin complements the stimulation which naturally occurs during sleep and thereby facilitates the nighttime release of HGH that is characteristic of youth.
How Will You Know Its Working?
Patients usually report improved sleep quality within the first few weeks of therapy. This usually comes along with improved mood and increased energy levels. After 3-6 months of therapy, most people report noticeable body changes like increased muscle tone and a leaner physique.
Like most peptide hormones, sermorelin takes about 6 months before full effects are noticed. Like HGH, sermoerlin is metabolized quickly and therefore requires daily dosing. Its action causes a chain reaction that results in elevated and sustained HGH and growth factor levels. So it does take some time to become optimal and see the benefits youre looking to achieve.
Do You Need To Take It Forever?
In many instances, no. Sermorelin has an ongoing effect in which HGH levels can be sustained after the last injection.Initially, like HGH, it needs to be injected every day. But once optimal results are achieved, you can often be switched to a maintenance protocol eliminating the need for daily injections and further reducing the cost of therapy.
What Are the Symptoms of HGH Deficiency?
A study of benefits include:
How Do You Get Started?
The starting place for any hormonal optimization program is a thorough evaluation including a blood draw to measure current levels and see if you are a candidate for therapy.
How long does it take to work?
Just like most peptide hormones, Sermorelin usually has a loading period of 3-6 months before full effects are noticed. Once injected, both Sermorelin and HGH are eliminated from then body very quickly and therefore need to be injected frequently. Its actions are dependent on a chain reaction of biological processes which result in elevated and sustained HGH and growth factors. It takes some time for levels to become optimal, and initiate the benefits we are seeking to achieve.
Unlike illegal human growth hormone, Sermorelin hGH is manufactured in U.S. based, FDA approved pharmacies. If the Doctor does not prescribe it to you, products that you found on the internet are manufactured outside of the U.S., without safety guidelines, and may contain unknown and dangerous fillers.Sermorelin Rejuvenative Therapy
Sermorelin Acetate Therapy is a fantastic therapy because it maintains the health of the organs of the body. It allows men and women to age more gracefully by working to prevent the frailness that so many associate with the aging process.
In addition to helping men and women feel better and stronger as they grow older, it also helps them look better too! The rejuvenating and muscle-strengthening capacities of therapy also apply to the skin. The muscles underneath the skins surface become stronger, tightening the skin and reducing wrinkles and deep lines on the face and body. This occurs in conjunction with the skin cells being able to hold more water and develop enhanced elasticity. Sermorelin is great for lessening wrinkles. Increased HGH Production also benefits the skin by reinforcing the collagen which holds the skin in place.
How Do Sermorelin Injections Encourage and Facilitate Weight Loss?
Sermorelin is highly effective at helping patients lose weight. Sermorelin is so effective at inducing weight loss because Human Growth Hormone stimulates the production of Insulin-like Growth Factor 1 (IGF-1). Higher levels of IGF-1 lead to higher levels of metabolism, which make it easier to lose weight more quickly when one controls calories.
Higher levels of metabolism also provide the body with more energy and endurance for aerobic exercise. The increased level of metabolism eliminates fat by both causing the body to burn fat without activity while also giving the patient the energy and motivation boost he or she needs to stick with a healthy exercise regimen.
Sermorelin Therapy vs. Human Growth Hormone Therapy
So if all of these medical issues are the result of Human Growth Hormone Deficiency, why take Sermorelin Acetate Injections? One advantage of Sermorelin Therapy as compared to Human Growth Hormone Therapies such as Humatrope and Somotropin is that Sermorelin does not suppress endogenous hormone production in the same way, because it is a precursor hormone. The body uses the Sermorelin that it needs to manufacture a healthy amount of Human Growth Hormone, but this does not overwhelm the system or cause it to produce excessive HGH.
Because Sermorelin cannot encourage the body to produce excess levels of Human Growth Hormone because of its location on the Pituitary-IGF-1 axis, this makes the risk of overdose, side-effects, and the potential for abuse significantly lower than with HGH. In fact, the biological pathway of Sermorelin prevents a few problems which can arise from Human Growth Hormone Replacement Therapy. Sermorelin Acetate Therapy does not have the same effect on blood sugar levels as HGH Replacement Therapy, eliminating the risk of High Blood Sugar and Low Blood Sugar (Hyperglycemia & Hypoglycemia) as a result of therapy.
Human Growth Hormone Overdose and Abuse has also been associated with the risk of sore joints or the development or advancement of Carpal Tunnel Syndrome. Sermorelin Acetate Therapy significantly reduces the risk of joint disorders because the therapy does not lead to excess levels of Growth Hormone present in the human body. This is another reason why Sermorelin Therapy may be a better option for older patients who suffer from a Growth Hormone Deficiency.
For those who want faster results, Human Growth Hormone Therapy may be the preferred choice, but most people are satisfied with the effectiveness of Sermorelin Injections, especially with the much-reduced risk of altering the bodys ability to manufacture Human Growth Hormone on its own. Some doctors may recommend taking Sermorelin Acetate injections in addition to Human Growth Hormone under some circumstances, to maximize the effectiveness of HGH therapy while preserving the bodys ability to naturally produce the hormone.
Who Should not take Sermorelin?
If you have a prescription or are currently taking corticosteroids such as Prednisone, it may interact poorly with Sermorelin Acetate. Also, if you are currently taking thyroid medicines such as Levothyroxine, you should also let your doctor know, as these medications can also result in unwanted drug interactions.
Those who have cancer should avoid using any medication or hormone therapy that encourages the production of Human Growth Hormone, as Human Growth Hormone can stimulate the production of cancer cells. Human Growth Hormone is effective at encouraging the growth of all cells in the body, even those that are cancerous.
Women that are pregnant should not take Sermorelin or any Human Growth Hormone Therapy unless it is recommended and approved by a doctor. In animal studies featuring doses of Sermorelin which were significantly higher than those typically used for women, it was shown that Sermorelin can induce minor physical birth defects in the fetus.
There has not been sufficient research conducted on the effect that Sermorelin has on the womb, though it appears as though the risks of modest usage of Sermorelin Acetate for the fetus are relatively low. Women that are nursing should avoid Sermorelin unless given approval by their physician. It is unclear whether this hormone can pass to the child through breast milk.
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